Resident Evil: The Final Chapter (2016)

In a flashback, it is revealed that Dr. James Marcus, the founder of the Umbrella Corporation, had a daughter, Alicia, who was dying of progeria. Desperate to save her, Marcus confiscates an untested embryonic Umbrella project created by his colleague Dr. Charles Ashford—the T-virus—and uses it on Alicia and others with the disease. After one child treated with the virus dies and becomes a zombie, Marcus orders the project be terminated and forbids Ashford from pursuing it. His partner, Dr. Alexander Isaacs, has Marcus murdered by Albert Wesker, adopts Alicia and takes over the Corporation. Alicia inherits her father’s 50% ownership. After being betrayed by Wesker in Washington D.C., Alice awakens. The Red Queen appears and tells her she has 48 hours to infiltrate the Hive, a facility beneath Raccoon City. The Umbrella Corporation has an airborne anti-virus that can kill every zombie, but is waiting for the last few remaining humans to be wiped out. As her body carries the virus, Alice does not expect to live after the mission.

While travelling, Alice is captured by Isaacs, learning the “Isaacs” she previously killed was a clone. She escapes his convoy and reaches Raccoon City, where she meets a group of survivors: Doc, Abigail, Christian, Cobalt, Razor, and Claire Redfield, who survived the attack on Arcadia. Isaacs’ convoy approaches, trailed by a horde of zombies. Alice and the group defeats them and retrieves Isaacs’ few human captives, though Cobalt dies in the process. Alice and crew enter the Hive, where Wesker is in control. He releases mutated guard dogs, killing Christian and a freed captive. The Red Queen appears to Alice and explains that her program is in conflict, as she can never hurt an Umbrella employee but also must value human life. She plays a video of Isaacs explaining to Umbrella’s executives a plan to release the T-virus, cleansing the world of humanity; many of the rich and powerful, including the company executives, are stored in cryogenic capsules in the Hive, with the intention of rebuilding the world following the resulting apocalypse.